Table 2.
Number of Aggregation Tests Outside the Target Range and Comparison of the Area Under the Curve (AUC) of the PL Chip.
| Test | Outside target range, n (%) | AUC-PL inside target, median (IQR) |
AUC-PL outside target, median (IQR) |
p | |
|---|---|---|---|---|---|
| MEA | ASPI-test a | 4 (7.8) | 69 (19-142) | 189 (49-324) | .197 |
| ADP-test a | 3 (5.5) | 69 (19-142) | 19, 161, 398* | .324 | |
| ADP and ASPI-test | 2 (3.3) | 69 (18-142) | 237, 425* | .008 | |
| LTA | ADP 20 µM a | 20 (40.0) | 31 (10-98) | 139 (73-208) | .01 |
| AA 2 mM a | 2 (9.0) | 31 (10-98) | 11, 83* | .968 | |
| AA and ADP | 8 (13.3) | 32 (11-113) | 161 (70-222) | .440 | |
*
Absolute values.
Abbreviations: AA, arachidonic acid; ADP, adenosine diphosphate; ASPI-test, acetylsalicylic acid-test; AUC-PL, area under the curve of the PL-chip; IQR, interquartile range; LTA, light transmission aggregometry; MEA, multiple electronic aggregometry.
a
Including cases of single low response only.