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. 2024 Nov 23;163(1):8. doi: 10.1007/s00418-024-02341-6

Table 1.

Patient demographics and clinical data across all groups [N − ve, N + ve, EOPE − ve, EOPE + ve, LOPE − ve, and LOPE + ve]

Patient data N – ve (n = 60) N + ve (n = 60) EOPE – ve (n = 60) EOPE + ve (n = 60) LOPE – ve (n = 60) Lope + ve (n = 60) p-value P value (across all groups)
Gestational age (weeks)

N − ve vs. EOPE − ve

N − ve vs. EOPE + ve

N − ve vs. LOPE − ve

N − ve vs. LOPE + ve

N + ve vs. EOPE − ve

N + ve vs. EOPE + ve

N + ve vs. LOPE − ve

N + ve vs. LOPE + ve

38.00 (37.00–39.00) 37.00 (36.00–39.00) 30.00 (25.75–34.50) 33.00 (30.00–35.00) 35.50 (34.00–37.00) 35.00 (33.00–36.00)

 < 0.0001****

0.0099**

 < 0.0001****

 < 0.0001****

 < 0.0001****

 < 0.0001****
Systolic BP (mmHg)
 N − ve vs. EOPE − ve  111.0 (106.0–116.8) 111.0 (105.0–117.0) 151.0 (143.0–160.0) 148.0 (136.0–161.0) 154.0 (146.5–173.0) 145.0 (141.8–153.3) ****  < 0.0001****
N − ve vs. EOPE + ve ****
N − ve vs. LOPE – ve ****
 N − ve vs. LOPE + ve ****
 N + ve vs. EOPE − ve ****
 N + ve vs. EOPE + ve ****
N + ve vs. LOPE − ve ****
 N + ve vs. LOPE + v ****
Diastolic BP (mmHg)
N − ve vs. EOPE − ve 71.00 (64.50–79.00) 70.00 (64.00–76.00) 95.50 (91.00–104.3) 92.00 (90.00–98.00) 106.0) 101.0 (94.00–108.0) 96.00 (91.00–98.25) ****  < 0.0001****
N − ve vs. EOPE + ve ****
N − ve vs. LOPE − ve ****
N − ve vs. LOPE + ve ***
N + ve vs. EOPE − ve ****
N + ve vs. EOPE + ve *
N + ve vs. LOPE − ve **
N + ve vs. LOPE + ve ****
Maternal weight (kg)
 LOPE − ve vs. LOPE + ve* 73.70 (63.25–97.77) 67.30 (55.25–85.38) 67.20 (60.25–91.00) 81.00 (68.48–87.90) 66.00 (55.75–81.00) 85.35 (69.90–95.25) * 0.2221*
Maternal age (years)
 N + ve vs. LOPE − ve 25 (22–30) 28 (25.00 – 31.00) 23 (20–27) 32 (25–37) 23 (19–26) 28 (25–34) ****  < 0.0001****
 EOPE − ve vs. EOPE + ve *
 EOPE − ve vs. LOPE + ve **
 EOPE + ve vs. LOPE – ve *
 LOPE − ve vs. LOPE + ve ***
Gestational weight (kg)
 N − ve vs. EOPE − ve 3.150 (2.975–3.585) 2.900 3.100 (2.600–3.550) 2.100 (1.625–2.538) 1.900 (1.300–2.500) 3.000 (2.723–3.213) (2.300–3.120)  < 0.0001 ****  < 0.0001****
 N − ve vs. EOPE + ve ****
 N + ve vs. EOPE − ve ****
 N + ve vs. EOPE + ve ****
 EOPE − ve vs. LOPE − ve ****
 EOPE − ve vs. LOPE + ve *
 EOPE + ve vs. LOPE − ve **

Across the population group (n = 180), the Kruskal-Wallis (K-W) test detected significance for maternal age (p < 0.0001), weight (p = 0.0221), systolic and diastolic pressure (p < 0.0001), and gestational weight and age (p < 0.0001). The Dunn's multiple comparison test further calculated the significance between the PE groups stratified by HIV, indicated in Table 1