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. 2024 Nov 23;150(12):509. doi: 10.1007/s00432-024-05973-2

Fig. 2.

Fig. 2

Elevated levels of SOX2 expression in cervical cancer, with high SOX2 expression indicating a better prognostic outcome. A Significant variability in SOX2 expression across different cervical cancer samples. B Prognostic differences in cervical squamous cell carcinoma with varying levels of SOX2 expression, where the high-expression group has a better prognosis. C A substantial prognostic disparity in cervical cancer patients with different levels of SOX2 expression, again favoring the high-expression group. D Tumor stemness assays reveal that the high SOX2 expression group exhibits greater tumor stemness compared to the low-expression group and normal tissue. E After adjusting the appropriate CUT OFF value, the relationship between SOX2 expression levels and prognosis becomes clearer. F According to the HPA database, SOX2 expression in cervical cancer tissues (Figs. 2, 3, 4) is significantly higher than in normal tissue (Fig. 1). *P < 0.05. **P < 0.01. ***P < 0.001. ****P < 0.0001