Table 8.
Correlation analysis of hematological phenotypes with age and gender in the thalassemia-only group (taking --SEA/αα as an example)a.
| Age groups | Gender | RBC ( × 1012/L) | Hb (g/L) | MCV (fL) | MCH (pg) | MCHC (g/L) | RDW-CV (%) | SF (ng/mL) |
|---|---|---|---|---|---|---|---|---|
| ≤18 years (n = 114) | 5.40 (5.03,5.79) | 106.00 (97.00,112.00) | 62.00 (60.00,64.50) | 19.50 (18.90,20.50) | 317.00 (308.00,321.00) | 15.80 (15.10,17.00) | 40.60 (27.73,59.09) | |
| male (n = 64) | 5.60 (4.99,5.76) | 107.00 (94.50,113.00) | 62.30 (60.35,65.25) | 20.00 (19.05,20.60) | 316.00 (307.50,322.50) | 16.40 (15.05,17.90) | 40.60 (32.80,59.50) | |
| female (n = 50) | 5.35 (5.00,5.80) | 105.50 (97.00,109.50) | 61.75 (59.35,64.33) | 19.30 (18.80,20.13) | 319.00 (307.75,320.25) | 15.50 (15.18,16.53) | 40.55 (24.20,58.90) | |
| ≥19 years (n = 338) | 5.20 (4.68,5.50) | 112.00 (1040.00,119.00) | 67.60 (65.00,70.00) | 21.70 (21.00,22.30) | 320.00 (313.00,326.00) | 15.50 (14.60,16.50) | 66.27 (31.75,128.88) | |
| male (n = 82) | 5.59 (5.08,6.69) | 127.00 (105.50,142.50) | 69.00 (65.50,70.50) | 21.90 (20.80,22.35) | 314.00 (310.00,323.00) | 15.80 (14.50,18.35) | 163.00 (117.44,246.09) | |
| female (n = 256) | 5.10 (4.66,5.40) | 110.00 (104.00,116.00) | 67.30 (65.00,69.50) | 21.55 (20.98,22.33) | 321.00 (313.00,326.00) | 15.45 (14.60,16.33) | 49.05 (25.65,89.81) | |
| Comparison of Hematological parameters between different age groupsa | ||||||||
| p1 | 0.041b | 0.005b | 0.000b | 0.000b | 0.036b | 0.107 | 0.016b | |
| Comparison of hematological parameters in males berween different age groupsa | ||||||||
| P2 | 0.238 | 0.004b | 0.000b | 0.000b | 0.869 | 0.538 | 0.000b | |
| Comparison of hematological parameters in females berween different age groupsa | ||||||||
| P3 | 0.015b | 0.066 | 0.000b | 0.000b | 0.042b | 0.621 | 0.460 | |
| Comparison of hematological parameters between male and female in each age groupa | ||||||||
| P4 (≦18 years of age group: Male VS Female) | 0.951 | 0.851 | 0.362 | 0.251 | 0.902 | 0.107 | 0.481 | |
| P5 (≥19 years of age group: Male VS Femal) | 0.001b | 0.001b | 0.171 | 0.833 | 0.026b | 0.350 | 0.000b | |
a
Age and hematological parameters were statistically described by median (P25,P75). hematological parameters were compared by Wilcoxon rank sum test, with 95 confidence intervals (two-sided).
b
p < 0.05.