Table 1. RMSD and RMSF average values of SARS-CoV-2 Mpro wild and mutated.

System	RMSD (nm)	RMSF (nm)
5RE4	0.15 ±0.02	0.08 ±0.03
A191V	0.16 ±0.02	0.08 ±0.03
G11A	0.14 ±0.02	0.08 ±0.04
N142S	0.16 ±0.02	0.08 ±0.03
R60C	0.14 ±0.01	0.08 ±0.03
R298A	0.17 ±0.03	0.09 ±0.03
S139A	0.15 ±0.02	0.08 ±0.03
T190I	0.17 ±0.02	0.08 ±0.03
Y54C	0.18 ±0.03	0.07 ±0.03

RMSD, Root-mean square deviation; RMSF, Root-mean square fluctuation; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; Mpro, main protease.