Table 1. Summary of diseased SNPs predicted from Meta-SNP in SARS-CoV-2 mutations.
| Mutation | PANTHER | PhD-SNP | SIFT | SNAP | Meta-SNP | RI | Profile |
|---|---|---|---|---|---|---|---|
| G11A | NA | Neutral | Disease | Disease | Neutral | F [G]=55% | |
| - | 0.312 | 0.03 | 0.655 | 0.256 | 5 | F [A]=0% | |
| Nali=46 | |||||||
| Y54C | NA | Neutral | Disease | Disease | Disease | F [Y]=64% | |
| - | 0.499 | 0 | 0.745 | 0.675 | 4 | F [C]=0% | |
| Nali=46 | |||||||
| R60C | NA | Neutral | Neutral | Disease | Neutral | F [R]=56% | |
| - | 0.435 | 0.16 | 0.630 | 0.323 | 4 | F [C]=0% | |
| Nali=47 | |||||||
| S139A | NA | Disease | Disease | Disease | Disease | F [S]=100% | |
| - | 0.535 | 0 | 0.79 | 0.73 | 5 | F [A]=0% | |
| Nali=47 | |||||||
| N142S | NA | Neutral | Neutral | Neutral | Neutral | F [N]=33% | |
| - | 0.189 | 0.7 | 0.47 | 0.193 | 6 | F [S]=4% | |
| Nali=47 | |||||||
| T190I | NA | Neutral | Neutral | Neutral | Neutral | F [T]=17% | |
| - | 0.214 | 0.34 | 0.39 | 0.197 | 6 | F [I]=4% | |
| Nali=46 | |||||||
| A191V | NA | Neutral | Neutral | Neutral | Neutral | F [A]=32% | |
| - | 0.066 | 1 | 0.3 | 0.064 | 9 | F [V]=26% | |
| Nali=46 | |||||||
| R298A | NA | Neutral | Neutral | Disease | Neutral | F [R]=30% | |
| - | 0.159 | 0.06 | 0.53 | 0.183 | 6 | F [A]=0% | |
| Nali=46 |
RI=Reliability Index between 0 and 10; F [X]=Frequency of residue X in the sequence profile; Nali: Number of aligned sequences in the mutated site.