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. 2024 Nov 11;15:1499340. doi: 10.3389/fphys.2024.1499340

TABLE 1.

Norepinephrine (NE) stimulates PVAT to release vasoactive factors to regulate vascular function.

Location of PVAT Stimulus PVAT-derived factors Effects Species Condition References
MA NE NO Anti-contraction Rat Physiological Bussey et al. (2018)
MA NE Adiponectin Anti-contraction Mouse Obesity Agabiti-Rosei et al. (2014)
TA; MA NE NO Anti-contraction Rat Sepsis Barp et al. (2020)
MA NE NO Anti-contraction Mouse Obesity Gil-Ortega et al. (2014)
MA NE Adiponectin Anti-contraction Mouse Physiological Lynch et al. (2013)
MA NE Adiponectin Anti-contraction Mouse Hypoxia Rosei et al. (2015)
MA NA Adiponectin Anti-contraction Rat Physiological Saxton et al. (2019b)
MA NE Adiponectin Anti-contraction Mouse Physiological Withers et al. (2017)
MA EFS and EX Adiponectin Anti-contraction Mouse Obesity and Physiological Saxton et al. (2021)
MA EFS Adiponectin Anti-contraction Mouse Physiological Saxton et al. (2018)
MA NE NO Anti-contraction Mouse Hypertension Persson, Marchetti, and Friederich-Persson, (2023)
MA NE NO Anti-contraction Rat Obesity Zaborska et al. (2016)

MA, mesenteric artery; TA, thoracic aorta; NO, nitric oxide; NE, norepinephrine; NA, noradrenaline; ADRB3, beta-3, adrenergic receptor; EFS, electrical field stimulation; EX, exercise.