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Diethyl butylmalonate relieves neuron degeneration in the hippocampus of female 5×FAD mice. Golgi-Cox staining was used to analyze the neuronal morphological variations in the cornu ammonis 1 (CA1) region of the hippocampus of female mice. (A) Representative images of pyramidal neurons. (B) Sholl analysis of dendritic branching complexity of pyramidal neurons. (C) Total neurite length per cell. n = 3, scale bars: 100 μm. Values are mean ± SEM. *p < 0.05, **p < 0.01, and ***p < 0.001.
