Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Nov 11;18:1480000. doi: 10.3389/fnins.2024.1480000

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2024 Yuan, Song, Xu, Liu, Zhang, Pan, Ding, Fu, Lin and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Diethyl butylmalonate ameliorates the neuroinflammation in the amygdala of 5×FAD female mice. (A) Representative immunofluorescent staining of the Iba-1 cells in the amygdala (n = 3). (B) The quantification of Iba-1 cells number in the amygdala (n = 3, 10 images per mouse per region, scale bar: 50 μm). (C) The ramification of microglia in the amygdala (n = 3, 10 images per mouse per region, scale bar: 50 μm). (D) The circularity of microglia in the amygdala (n = 3, 10 images per mouse per region, scale bar: 50 μm). (E–G) The mRNA expression of IL-1β, IL-6 and TNF-α the amygdala (n = 4). Con + Veh, control mice with vehicle control treatment; Con + DBM, control mice with DBM treatment; 5×FAD + Veh, 5×FAD mice with vehicle control treatment; 5×FAD + DBM: 5×FAD mice with DBM treatment. Values are mean ± SEM. ^*p < 0.05, ^**p < 0.01, and ^***p < 0.001.