FIGURE 5.

Brain amino acid and neurotransmitter metabolites in treated PKU mice. (A) Phe, Tyr, and Trp amino acid concentration in wild‐type (WT) and PKU controls and male and female treated mice. (B) Serotonin, 5‐hydroxyindoleacetic acid (5‐HIAA), dopamine, homovanillic acid (HVA), and norepinephrine neurotransmitter concentration in WT and PKU controls and male and female treated mice. Dashed lines represent the mean concentration in PKU mouse brains. Statistics: one‐way ANOVA, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.