In vitro anticancer activity of the products 2a–j against TK-10 and A549 cancer cells.
| Compounds | IC50 (μg mL−1) | |
|---|---|---|
| TK-10 | A549 | |
| 2a | ≥100 | ≥100 |
| 2b | ≥100 | 66.9 ± 0.7 |
| 2c | 11.7 ± 2.3 | 33.4 ± 0.8 |
| 2d | ≥100 | ≥100 |
| 2e | 1.0 ± 0.1 | 2.4 ± 0.3 |
| 2f | ≥100 | ≥100 |
| 2g | 5.1 ± 0.7 | 10.9 ± 1.2 |
| 2h | 2.3 ± 0.1 | 4.7 ± 0.2 |
| 2i | ≥100 | 44.7 ± 3.6 |
| 2j | 1.4 ± 0.1 | 1.0 ± 0.1 |
| Doxorubicin | 1.4 ± 0.4 | 1.9 ± 0.7 |