TABLE 4.
Demographic characteristics results and fetal weight analysis by gestational age.
| Demographic characteristics results | Median | Mean | Std dev | |
|---|---|---|---|---|
| Maternal age a (n = 4031) | ||||
| Min | 15 | 30 | 30.06 | 5.86 |
| Max | 50 | |||
| Length of gestation b (N = 3836) | ||||
| Min | 12 | 39 | 37.24 | 5.16 |
| Max | 44 | |||
| Total of pregnancy (gravidity) c (N = 3002) | ||||
| Min | 0 | 1 | 1.29 | 1.57 |
| Max | 19 | |||
| Fetal sex according to COA class | Results effectif (%) | |||
|---|---|---|---|---|
| Male | Female | Indeterminate | Not known | |
| Anophtalmia/microphthalmia | 598 (49.5%) | 586 (48.6%) | 7 (0.6%) | 15 (1.3%) |
| Congenital cataract and lens anomalies | 825 (52.3%) | 750 (47.5%) | 1 (0.1%) | 2 (0.1%) |
| Macrophthalmia | 12 (66.7%) | 6 (33.3%) | 0 (0%) | 0 (0%) |
| Congenital anomalies of the anterior segment | 558 (53.7%) | 480 (46.2%) | 0 (0%) | 2 (0.2%) |
| Congenital anomalies of the posterior segment | 354 (55.9%) | 278 (43.9%) | 0 (0%) | 1 (0.2%) |
| Congenital glaucoma | 229 (59.2%) | 158 (40.8%) | 0 (0%) | 0 (0%) |
| Dysplasia of the septum and optic pathways | 66 (54.1%) | 55 (45.1%) | 0 (0%) | 1 (0.8%) |
| Coloboma | 348 (52.8%) | 311 (47.2%) | 0 (0%) | 0 (0%) |
| Fetal weight analysis by gestational age (ALL) | |
|---|---|
| N = 4585 | |
| < 3rd percentile | 817 (17.8%) |
| 3rd–97th percentile | 3601 (78.5%) |
| > 97th percentile | 167 (3.6%) |
| Intrauterine fetal growth restriction (IUFR) subgroup (817) | |
| 603 < 1st percentile (73.8%) | |
| 214 1st–3rd percentile (26.2%) | |
| Distribution of weight < 3rd percentile for each COA class (N = 817) | |
| Class 1: anophtalmia/microphthalmia | 291 (35.6%) |
| Class 2: congenital cataract and lens anomalies | 195 (23.9%) |
| Class 3: macrophthalmia | 6 (0.7%) |
| Class 4: congenital anomalies of the anterior segment | 177 (21.7%) |
| Class 5: congenital anomalies of the posterior segment | 107 (13.1%) |
| Class 6: congenital glaucoma | 42 (5.1%) |
| Class 9: dysplasia of the septum and optic tract | 8 (1.0%) |
| Class 10: coloboma | 104 (12.7%) |
| Proportion of IUFR ion each COA class | |
| Class 1: anophtalmia/microphthalmia (N = 1106) | 291 (26.3%) |
| Class 2: congenital cataract and lens anomalies (N = 1407) | 195 (13.9%) |
| Class 3: macrophthalmia (N = 17) | 6 (35.3%) |
| Class 4: congenital anomalies of the anterior segment (N = 981) | 177 (18.0%) |
| Class 5: congenital anomalies of the posterior segment (N = 590) | 107 (18.1%) |
| Class 6: congenital glaucoma (N = 350) | 42 (12.0%) |
| Class 9: dysplasia of the septum and optic tract (N = 114) | 8 (7.0%) |
| Class 10: coloboma (N = 634) | 104 (16.4%) |
| Fetal weight analysis by gestational age in LIVE BIRTH only | |
|---|---|
| N = 4379 | |
| < 3rd percentile | 742 (16.9%) |
| 3rd–97th percentile | 3486 (79.6%) |
| > 97th percentile | 151 (3.5%) |
| IUFR subgroup (742) | |
| 542 < 1st percentile (73.1%) | |
| 200 1st–3rd percentile (26.9%) | |
| Distribution of weight < 3rd percentile for each COA class (N = 742) | |
| Class 1: anophtalmia/microphthalmia | 250 (33.7%) |
| Class 2: congenital cataract and lens anomalies | 185 (24.9%) |
| Class 3: macrophthalmia | 3 (0.4%) |
| Class 4: congenital anomalies of the anterior segment | 170 (22.9%) |
| Class 5: congenital anomalies of the posterior segment | 98 (13.2%) |
| Class 6: congenital glaucoma | 42 (5.7%) |
| Class 9: dysplasia of the septum and optic tract | 8 (1.1%) |
| Class 10: coloboma | 94 (12.7%) |
| Proportion of IUFR ion each COA class | |
| Class 1: anophtalmia/microphthalmia (N = 981) | 250 (25.5%) |
| Class 2: congenital cataract and lens anomalies (N = 1383) | 185 (13.4%) |
| Class 3: macrophthalmia (N = 14) | 3 (21.4%) |
| Class 4: congenital anomalies of the anterior segment (N = 964) | 170 (17.6%) |
| Class 5: congenital anomalies of the posterior segment (N = 566) | 98 (17.3%) |
| Class 6: congenital glaucoma (N = 349) | 42 (12.0%) |
| Class 9: dysplasia of the septum and optic tract (N = 105) | 8 (7.6%) |
| Class 10: coloboma (N = 611) | 94 (15.4%) |
| Fetal weight analysis by gestational age (other than livebirth) | |
|---|---|
| N = 206 | |
| < 3rd percentile | 75 (36.4%) |
| 3rd–97th percentile | 115 (55.8%) |
| > 97th percentile | 16 (7.8%) |
| IUFR subgroup (75) | |
| 61 < 1st percentile (81.3%) | |
| 14 1st–3rd percentile (18.7%) | |
| Distribution of weight < 3rd percentile for each COA class (N = 75) | |
| Class 1: anophtalmia/microphthalmia | 41 (54.7%) |
| Class 2: congenital cataract and lens anomalies | 10 (13.3%) |
| Class 3: macrophthalmia | 3 (4.0%) |
| Class 4: congenital anomalies of the anterior segment | 7 (9.3%) |
| Class 5: congenital anomalies of the posterior segment | 9 (12.0%) |
| Class 6: congenital glaucoma | 0 (0%) |
| Class 9: dysplasia of the septum and optic tract | 0 (0%) |
| Class 10: coloboma | 10 (13.3%) |
| Proportion of IUFR ion each COA class | |
| Class 1: anophtalmia/microphthalmia (N = 125) | 41 (32.8%) |
| Class 2: congenital cataract and lens anomalies (N = 24) | 10 (41.6%) |
| Class 3: macrophthalmia (N = 3) | 3 (100%) |
| Class 4: congenital anomalies of the anterior segment (N = 17) | 7 (41.2%) |
| Class 5: congenital anomalies of the posterior segment (N = 24) | 9 (37.5%) |
| Class 6: congenital glaucoma (N = 1) | 0 (0%) |
| Class 9: dysplasia of the septum and optic tract (N = 9) | 0 (0%) |
| Class 10: coloboma (N = 23) | 10 (43.5%) |
a
One registry excluded.
b
Two registers excluded.
c
Four registers excluded.