FIGURE 7.

Presence of EYFP led to reduced HCN2 and FBP2 protein levels in gastrocnemius skeletal muscle. Significantly reduced protein‐level expressions of (A) HCN2 in the ChR2‐EYFP muscle and (B) FBP2 in both ChR2‐EYFP and ChR2‐only muscles were observed, compared with ChR2‐only and WT muscles, respectively. (C) ACTN3 protein expression was significantly higher in ChR2‐only muscle compared with WT and ChR2‐EYFP muscles. Error bars denote means ± SD. WT group included n = 1 ChR2‐EYFP^fl/fl and n = 2 ChR2‐only^fl/fl mice (all cre‐negative).