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. 2024 Nov 7;14(4):1711–1728. doi: 10.3390/jox14040091

Figure 5.

Figure 5

Long-term impact of expression of PS-IONPs on NF-κB nuclear factor protein expression in the liver of mice with a persistent inflammatory state in comparison to the control groups. Experimental group: “+/+”—animals with a persistent inflammatory state (zymosan: 7 cycles of 18 µg/kg body weight, PS-IONPs: 50 µmol Fe/kg body weight). Control groups: “−/−”—animals without persistent inflammation and no intravenous PS-IONP injection, and “−/+”—animals without persistent inflammation but with intravenous injection of PS-IONPs, “+/−”—animals with persistent inflammation but without intravenous injection of PS-IONPs. Protein expression is presented relative to the housekeeping proteins β-actin or GAPDH (dots) and as mean and standard deviation of the mean; * p < 0.05, ** p < 0.01 (Mann–Whitney U-test), # not determined.