TABLE 1.
Baseline characteristics
| COPD (n=42) | Control (n=14) | p-value | |
|---|---|---|---|
| Anthropometric data | |||
| Age (years) | 68.5±9.1 | 60.8±9.5 | 0.009 |
| Female sex (%) | 45.24 | 57.14 | 0.44 |
| BMI (kg·m−2) | 26.3±4.9 | 25.9±3.6 | 0.76 |
| Spirometry and lung volumes | |||
| FEV1 (L) | 1.46±0.58 | 3.10±0.97 | <0.001 |
| FEV1 (Z-score) | −2.67±1.17 | 0.23±1.10 | <0.001 |
| FVC (L) | 3.07±0.85 | 4.10±1.19 | <0.001 |
| FVC (Z-score) | −0.72±1.14 | 0.44±1.04 | 0.002 |
| FEV1/FVC | 47.1±12.5 | 75.5±5.05 | <0.001 |
| FEV1/FVC (Z-score) | −3.28±1.07 | −0.39±0.68 | <0.001 |
| TLC (L) | 6.26±1.17 | 6.39±1.35 | 0.728 |
| TLC (Z-score) | 0.58±1.03# | −0.37±1.04 | 0.52 |
| FRC (Z-score) | 1.68±1.15# | 0.56±0.95 | 0.002 |
| FRC/TLC (Z-score) | 1.29±1.45# | −0.05±1.52 | 0.005 |
| RV (Z-score) | 1.53±1.01# | 0.42±1.02 | 0.001 |
| RV/TLC (Z-score) | 1.86±1.15# | 0.48±1.19 | <0.001 |
Values are presented as mean±sd, unless otherwise stated. Bold indicates statistical significance. BMI: body mass index; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; TLC: total lung capacity; FRC: forced residual capacity; RV: residual volume. #: data missing for 1 patient.