Table 3.

Multivariate cox proportional hazard regression analyses of factors affecting all-cause mortality and CMML-related mortality among US patients between 2000 and 2017.

Characteristics	Overall Mortality. Adjusted Proportional Hazard Ratio (95% Confidence Interval)	CMML Mortality. Adjusted Proportional Hazard Ratio (95% Confidence Interval)
Gender
Female	1	1
Male	1.22 (1.13–1.32) **	1.24 (1.13–1.35) **
Age at diagnosis, y.o
0–39	1	1
40–59	1.26 (0.87–1.82)	1.37 (0.90–2.07)
60–79	2.39 (1.68–3.41) **	2.29 (1.53–3.41) **
80+	3.65 (2.55–5.24) **	3.01 (1.99–4.53) **
Race
Non-Hispanic white	1	1
Non-Hispanic black	1.13 (0.97–1.32)	1.13 (0.94–1.36)
Hispanic	1.03 (0.89–1.17)	1.08 (0.93–1.26)
Other	1.05 (0.92–1.21)	1.06 (0.89–1.25)
Living area
Counties in metropolitan areas of 1 million persons	1	1
Counties in metropolitan areas of 250,000 to 1 million persons	1.15 (1.05–1.26) **	1.18 (1.06–1.32) **
Counties in metropolitan areas of 250,000 persons	0.99 (0.86–1.13)	1.01 (0.86–1.19)
Nonmetropolitan counties adjacent to a metropolitan area	0.99 (0.86–1.16)	1.01 (0.84–1.21)
Nonmetropolitan counties not adjacent to a metropolitan area	1.13 (0.95–1.34)	1.19 (0.97–1.46)
Income per year
USD <55,000	1	1
USD 55,000–64,999	0.86 (0.76–0.98) *	0.93 (0.79–1.08)
USD 65,000–74,999	0.89 (.077–1.02)	0.93 (0.79–1.09)
USD 75,000+	0.84 (0.73–0.96) *	0.91 (0.77–1.07)
Marital status
Married	1	1
Single	1.31 (1.16–1.47) **	1.30 (1.13–1.49) **
Divorced/Separated	1.11 (0.98–1.27)	1.06 (0.91–1.24)
Widowed	1.28 (1.16–1.41) **	1.27 (1.13–1.43) **
Chemotherapy for CMML
No	1	1
Yes	1.51 (1.39–1.62) **	1.91 (1.75–2.08) **
Radiation
No	1	1
Yes	0.89 (0.65–1.23)	0.93 (0.65–1.31)

** p < 0.01, * p < 0.05.