Table 6. Assessment of changes in number of patient’s symptom grading on 4-point scale between groups.

The data was analyzed by using the Chi-square test. Significant at <0.05.

* - Denotes a significant value in the comparison between the EnMax and Placebo groups.

 # - Denotes a significant value in the comparison between the EnMax and Marketed reference groups. 

Changes in symptom grading on 4-point scale (number of patient’s)
Visits	Visit 1				Visit 2				Visit 3					Visit 4
Score	0	1	2	3	0	1	2	3	0	1	2	3	0		1	2	3
Symptoms	EnMax
Erythema	8	8	10	0	13	7	6	0	20*	6	0	0	25*		1	0	0
Local irritation	4	14	8	0	10	16	0	0	22*#	4	0	0	24*#		2	0	0
Discharge (Pus/blood)	13	12	1	0	24*#	2	0	0	23*#	3	0	0	26*		0	0	0
Induration	6	11	9	0	12	13	1	0	18*	8	0	0	24*		2	0	0
Tenderness	4	15	7	0	17#	9	0	0	24*#	2	0	0	25*		1	0	0
Placebo
Erythema	9	13	4	0	9	15	2	0	11	15	0	0	12		14	0	0
Local irritation	2	17	7	0	4	18	4	0	7	18	1	0	10		16	0	0
Discharge (Pus/blood)	11	14	1	0	13	13	0	0	15	11	0	0	18		8	0	0
Induration	5	15	6	0	6	18	2	0	10	16	0	0	14		12	0	0
Tenderness	7	13	6	0	10	15	1	0	11	15	0	0	13		13	0	0
Marketed reference
Erythema	2	8	3	0	4	8	1	0	7	6	0	0	11		2	0	0
Local irritation	1	9	3	0	3	10	0	0	7	6	0	0	8		5	0	0
Discharge (Pus/blood)	7	5	1	0	8	5	0	0	8	5	0	0	12		1	0	0
Induration	5	6	2	0	6	5	2	0	7	6	0	0	9		4	0	0
Tenderness	2	11	0	0	3	10	0	0	6	7	0	0	10		3	0	0