Injection of liposomes containing PE 18:0/22:6 reduced exploration in the open field. (A) The central and peripheral regions. The area of the central region (Ac, white area) is the same as that of the peripheral region (Ap, purple area). (B) Total distance traveled. (C) Distance traveled in the central region. (D) Distance traveled in the peripheral region. (E) Time spent in the central region. (F) Twenty-five equal areas for counting crossings. The radius of the smallest circle is 1/3 the radius of the largest circle (r), and the radius of the medium-sized circle is 2/3 the radius of the largest circle. The yellow region is divided into 8 equal areas, and the red region is divided into 16 equal areas. (G) Number of area crossings. Bars presented as mean ± SE. The rat numbers in each group were as follows: saline (n = 11), egg PC (n = 10), PC 18:0/22:6 (n = 9), PE 18:0/22:6 (n = 9), PC P-18:0/22:6 (n = 9), and PE P-18:0/22:6 (n = 9). Differences were evaluated using Hsu’s MCB test.