Table 4.

Comparison of outcomes for community hospital patients vs academic hospital patients by regression analysis

	Unadjusted analysis		Adjusted analysis
Outcome	Odds/hazard ratio (95% CI)	P value	Odds/hazard ratio (95% CI)	P value
Primary outcome: 28-day mortality	1.43 (0.98, 2.07)	0.062	1.23 (0.81, 1.87)	0.332
In-hospital death	1.91 (1.28, 2.85)	0.001	1.38 (0.90, 2.11)	0.142
Time to death	1.63 (1.11, 2.40)	0.013	1.20 (0.79, 1.82)	0.389
Admitted to ICUa	0.94 (0.70, 1.26)	0.669	1.17 (0.83, 1.64)	0.367
Organ support while hospitalized
Invasive mechanical ventilation	0.98 (0.68, 1.41)	0.909	1.28 (0.86, 1.92)	0.226
RRT	1.36 (0.68, 2.75)	0.386	1.68 (0.76, 3.71)	0.197
Vasopressors	1.07 (0.75, 1.51)	0.723	1.19 (0.81, 1.75)	0.387
Organ support during first 14 days
Invasive mechanical ventilation	1.01 (0.70, 1.45)	0.978	1.33 (0.88, 2.00)	0.176
RRT	1.38 (0.65, 2.92)	0.402	1.77 (0.76, 4.10)	0.182
Vasopressors	1.06 (0.74, 1.51)	0.752	1.18 (0.80, 1.75)	0.398
Septic shock	1.09 (0.71, 1.67)	0.704	1.25 (0.78, 2.01)	0.346
Acute respiratory distress syndrome	2.83 (1.74, 4.59)	<0.001	3.13 (1.87, 5.24)	<0.001
Acute kidney injury	1.53 (1.15, 2.04)	0.004	1.23 (0.89, 1.70)	0.199
Acute cardiac injury	1.88 (1.05, 3.37)	0.034	2.53 (1.33, 4.83)	0.005
	Unadjusted analysis		Adjusted analysis
Outcome	Difference in median/mean (95% CI)	P value	Difference in median/mean (95% CI)	P value
Hospital length of stay	1.0 (0.2, 1.9)	0.021	0.5 (-0.2, 1.3)	0.173
ICU length of stay	3.0 (0.3, 5.7)	0.031	1.7 (-1.9, 5.3)	0.363
DAFa first 14 days
Invasive mechanical ventilation	-0.6 (-1.0, -0.2)	0.003	-0.5 (-1.0, -0.1)	0.020
RRTa or dialysis	-0.7 (-1.1, -0.3)	<0.001	-b
Vasopressors	-0.6 (-1.0, -0.2)	0.003	-0.4 (-0.8, 0.0)	0.056

^aDAF = days alive and free, ICU = intensive care unit, RRT = renal replacement therapy

^bAdjusted regression analysis was not feasible numerically as few patients received renal replacement therapy during the first 14 days