Fig. 1.
Flowchart of data analysis. a SUVmax, SUVmean, MTV, and TLG were measured semi-automatically at the threshold of 40% on PET images. b Ktrans, Kep, and Ve were generated by standard Tofts pharmacokinetic model. c IHC staining and analysis of mismatch repair deficiency proteins. d Co-evolution analysis of glucose metabolism and blood flow perfusion in endometrial cancer. SUVmax maximum standardized uptake value, SUVmean mean standardized uptake value, MTV metabolic tumor volume, TLG total lesion glycolysis, Ktrans transfer constant, Kep efflux rate, Ve extravascular extracellular volume, IHC Immunohistochemistry