Table 1.
Demographic and clinical characteristics of study patients
| Patients characteristics | Control N = 20 |
RVO N = 20 |
Subgroups of RVO | ||
|---|---|---|---|---|---|
| CRVO N = 6 |
BRVO N = 14 |
P-values BRVO vs. CRVO |
|||
| Age, median (Q1;Q3) | 66.50 (63.50; 70.00) | 59.00 (54.50; 67.00)*a | 58.50 (57.00; 63.00) | 59.00 (52.00; 69.00) | 0.968 |
| Female (%)b | 50 | 60 | 83.33 | 50 | 0.163 |
| Hypertension (%)b | 40 | 55 | 16.66 | 71.43 | 0.111 |
| Diabetes (%)b | 10 | 10 | 16.66 | 7.14 | 0.515 |
| Smoking (%)b | 25 | 15 | 16.66 | 14.29 | 0.891 |
| BMI, median (Q1;Q3), kg/m2 | 22.97 (19.57; 25.46) | 24.34 (22.18; 27.51) | 23.89 (21.30; 24.34) | 25.51 (23.05; 28.13) | 0.274 |
| BCVA, median (Q1;Q3) | 0.52 (0.35; 1.35) | 0.92 (0.65; 1.05) | 1.00 (1.00; 1.10) | 0.92 (0.60; 1.00) | 0.312 |
| CRT, median (Q1;Q3) | 220.00(198.50;237.50) | 550.00 (454.50;660.00)**a | 628.00 (573.00;778.00)**c | 516.00 (425.00;595.00)**c | 0.179 |
| FAZ, median (Q1;Q3) | \ | 0.22 (0.12; 0.32) | 0.21 (0.12; 0.33) | 0.22 (0.11; 0.30) | 0.841 |
| PERIM, median (Q1;Q3) | \ | 2.07 (1.43; 2.24) | 2.17 (1.38; 2.29) | 1.93 (1.46; 2.17) | 0.659 |
| ILM-IPL, median (Q1;Q3) | \ | 89.00 (68.00; 149.81) | 118.31 (83.00; 265.05) | 89.00 (59.14; 131.00) | 0.353 |
| SVD, median (Q1;Q3) | \ | 45.00 (43.75; 47.55) | 44.70 (41.00; 46.90) | 45.05 (44.40; 47.60) | 0.602 |
| DVD, median (Q1;Q3) | \ | 44.45 (43.30; 47.23) | 44.88 (44.00; 48.00) | 44.10 (40.70; 46.46) | 0.353 |
* p < 0.05; ** p < 0.01
a, Mann–Whitney U test analyzed controls and RVO patients; b, Chi-square test; c, Kruskal-Wallis test analyzed controls, CRVO, and BRVO patients followed by Bonferroni correction
BMI: body mass index; BCVA: best corrected visual acuity, logMAR; CRT: central retinal thickness; FAZ: foveal avascular zone; PERIM: perimeter of foveal avascular zone; ILM-IPL: inner limiting membrane-inner plexiform layer; SVD: superficial capillary plexus vessel density; DVD: deep capillary plexus vessel density; BRVO: branch retinal vein occlusion; CRVO: central retinal vein occlusion; RVO: retinal vein occlusion