Fig. 5.

Limiting cubic splines of PPCV for heart failure outcomes. A is not-group, Adjusted relative hazard of heart failure by the continuous level pulse pressure coefficient of variation of (PPCV). The reference point is PPCV of 12.96%. The solid lines represent the hazard ratios across the spectrum of PPCV. The shaded regions represent the upper and lower bounds of the 95% confidence interval. P-values reflect adjusted trends (accounting for Baseline DBP, RISK10YRS, SCREAT, AGE, UMALCR, N_AGENTS, SUB_CLINICALCVD). B is INTENSIVE group, the reference point is PPCV of 6.98% and 12.96%. C is AGE group, the reference point is PPCV of 12.96%3 and 51.71%. D is SUB_CLNICALCVD group, the reference point is PPCV of 12.96%. Other group graphs are also based on the agreement model and reflect the same trend