Table 2.
Univariate and multivariate cox regression tables of PPCV
| Characteristic | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| PPCV constructed as continuous variables | ||||||
| PPCV | 1.032 | 1.018–1.046 | < 0.001 | 1.030 | 1.016–1.044 | < 0.001 |
| AGE | 1.099 | 1.083–1.117 | < 0.001 | 1.066 | 1.046–1.086 | < 0.001 |
| RISK10YRS | 1.046 | 1.036–1.056 | < 0.001 | 1.022 | 1.011–1.034 | < 0.001 |
| Baseline DBP | 0.955 | 0.944–0.966 | < 0.001 | 0.988 | 0.975–1.000 | 0.053 |
| SCREAT | 3.502 | 2.785–4.405 | < 0.001 | 2.299 | 1.733–3.050 | < 0.001 |
| UMALCR | 1.001 | 1.001–1.001 | < 0.001 | 1.001 | 1.001–1.001 | < 0.001 |
| N_AGENTS* | ||||||
| 1 | 1.115 | 0.553–2.246 | 0.762 | 1.008 | 0.493–2.061 | 0.982 |
| 2 | 1.805 | 0.931–3.503 | 0.081 | 1.384 | 0.698–2.747 | 0.352 |
| 3 | 3.542 | 1.835–6.836 | < 0.001 | 2.133 | 1.072–4.247 | 0.031 |
| ≥ 4 | 3.582 | 1.676–7.653 | 0.001 | 2.373 | 1.083–5.202 | 0.031 |
| SUB_CLINICALCVD* | ||||||
| Yes | 3.162 | 2.401–4.166 | < 0.001 | 1.965 | 1.475–2.616 | < 0.001 |
| PPCV as a grouping variable | ||||||
| PPCV* | ||||||
| 15.0% < PPCV < 20.0% | 1.250 | 0.905–1.728 | 0.175 | 1.297 | 0.937–1.797 | 0.117 |
| PPCV ≥ 20.0% | 2.507 | 1.770–3.552 | < 0.001 | 2.636 | 1.855–3.744 | < 0.001 |
| AGE | 1.099 | 1.083–1.117 | < 0.001 | 1.063 | 1.044–1.083 | < 0.001 |
| RISK10YRS | 1.046 | 1.036–1.056 | < 0.001 | 1.023 | 1.011–1.035 | < 0.001 |
| Baseline DBP | 0.955 | 0.944–0.966 | < 0.001 | 0.985 | 0.972–0.997 | 0.019 |
| SCREAT | 3.502 | 2.785–4.405 | < 0.001 | 2.293 | 1.728–3.044 | < 0.001 |
| UMALCR | 1.001 | 1.001–1.001 | < 0.001 | 1.001 | 1.001–1.001 | < 0.001 |
| N_AGENTS* | ||||||
| 1 | 1.115 | 0.553–2.246 | 0.762 | 1.001 | 0.489–2.046 | 0.999 |
| 2 | 1.805 | 0.931–3.503 | 0.081 | 1.330 | 0.670–2.642 | 0.415 |
| 3 | 3.542 | 1.835–6.836 | < 0.001 | 2.085 | 1.047–4.153 | 0.037 |
| ≥ 4 | 3.582 | 1.676–7.653 | 0.001 | 2.295 | 1.046–5.036 | 0.038 |
| SUB_CLINICALCVD* | ||||||
| Yes | 3.162 | 2.401–4.166 | < 0.001 | 1.966 | 1.478–2.615 | < 0.001 |
We conducted univariate Cox regression analysis on all baseline variables. Variables with a p value less than 0.2 were selected for further Cox regression analysis. Subsequently, variables with a p-value greater than 0.05 and a change in the hazard ratio (HR) value for PPCV (after eliminating the variable) less than 10% were eliminated. Finally, we identified PPCV, AGE, RISK10YRS, Baseline DBP, SCREAT, UMALCR, N_AGENTS, SUB_CLINICALCVD as the significant variable. * N_AGENTS with 0 prescription drugs as the control group, SUB_CLINICALCVD with no history of clinical CVD as the control group, and PPCV with 0 < PPCV ≤ 15.0% as the control group