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. Author manuscript; available in PMC: 2024 Nov 25.
Published in final edited form as: Nat Biomed Eng. 2023 Nov 30;8(4):380–396. doi: 10.1038/s41551-023-01143-w

Extended Data Figure 5: Phenotypic analysis of B7-H3-CAR T cells following stimulation with A549 WT.

Extended Data Figure 5:

B7-H3-CAR+, CAR+Zip2R+, or CAR+Zip7R+ T cells were stimulated twice with A549 WT. CAR positive or CAR and ZipR positive T cells were quantified by flow cytometry pre and post 2nd stimulation (stim) and CD4 and CD8 positive T cells post 2nd stim (N=2 donors).

(a) Percent CAR+ or CAR+ZipR+ cells pre and post 2nd stim (ns: nonsignificant, ***p<0.001, paired t-test). (b) Percent CD4+ (left panel) or CD8+ (right panel) cells post 2nd stimulation (**p<0.01, ***p<0.001, paired t-test).