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. Author manuscript; available in PMC: 2024 Nov 25.
Published in final edited form as: Nat Biomed Eng. 2023 Nov 30;8(4):380–396. doi: 10.1038/s41551-023-01143-w

Extended Data Figure 10: Transcriptomic analysis of CD4+ CAR.ZipR T cells by scRNAseq.

Extended Data Figure 10:

(a) GSEA of unstimulated or stimulated CD4+ CAR and CAR.ZipR T cell populations. (b) Expression of memory, effector/cytotoxicity, inhibition/exhaustion, and activation markers in unstimulated or stimulated CD4+ CAR and CAR.ZipR T cell populations. (c) Expression of selected genes in unstimulated or stimulated CD4+ CAR and CAR.ZipR T cell populations (Wilcoxon rank sum test with Bonferroni correction; ****adjusted p value < 0.0001 and log2 FC > 0.5 or < −0.5).