Figure 10.

The effects of the CUL1-plasmid on lung tissue inflammation and oxidative stress response. (a–e) Levels of inflammatory factors, such as TNF-α, IL-1β, IL-6, IL-13, and MMP-12, detected in BALF samples using ELISA. (f–h) ROS, MDA, and SOD levels in lung tissues. **P < 0.01. BALF, bronchoalveolar lavage fluid; CUL1, cullin-1; ELISA, enzyme-linked immunosorbent assay; IL-1β, interleukin-1β; IL-6, interleukin-6; IL-13, interleukin-13; MDA, malondialdehyde; MMP-12, matrix metalloproteinase-12; ROS, reactive oxygen species; SOD, superoxide dismutase; TNF-α, tumor necrosis factor-α.