Figure 8.

(a) Control, (b) 10 µM DN and OA, (c) 20 µM DN and OA, and (d) 30 µM DN and OA. According to the results of the cell cycle trials, co-treating A549 cells with DN and OA at varying doses caused the cells to terminate in the G2/M phase, indicating that the use of DN + OA together inhibited cell growth by arresting the cell cycle. (e) Statistical evaluation of assays for cell apoptosis. The data are shown as mean value ± SE. Mean significant difference (*P < 0.05, **P < 0.01) compared with the control.