Skip to main content
. 2024 Nov 14;121(47):e2413737121. doi: 10.1073/pnas.2413737121

Fig. 6.

Fig. 6.

SMT of MR. (A) Temporal projection of an MR SMT movie (Left) overlaid with tracks (Right). (Scale bar 5 μm.) (B) Representative tracks for MR in the dominant lowest mobility groups. (Left) MR/Aldo group 1 tracks in GRKO cells, (center) MR/Aldo group 2 tracks in GRKO cells, (Right) MR/Aldo group 1 tracks in parental cells. Note that MR/Aldo in parental cells exhibits a very small fraction of group 2 tracks (see also panel D). (C) Distribution of MR mean squared displacement (MSD) at a timelag of 0.8 s, obtained by iteratively fitting the van Hove correlation (vHc) function using the Richardson-Lucy algorithm for each of the four conditions—GRKO-Aldo (green solid line), parental Aldo (black dashed line), GRKO-Cort (blue solid line), parental-Cort (orange dashed line). (D) Population fractions for the different mobility groups for the indicated condition. Ncells/Ntracks: 51/1,878 (GRKO MR/Aldo), 51/2,000 (GRKO MR/Cort), 57/2,419 (parental MR/Aldo), 60/2,036 (parental MR/Cort). Recordings of cells were collected on two separate days for each condition.