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. 2024 Oct 30. Online ahead of print. doi: 10.1039/d4md00450g

Compilation of ongoing research on thiophene derivatives for the development of anti-oxidant agents.

Compound code Indication Biological target assay Mechanism Status Ref.
66 Antioxidant agent DNA damage caused by bleomycin By scavenging free ROS (reactive oxygen species) and reactive nitrogen species Preclinical 140
67 Antioxidant agent DNA damage caused by bleomycin By scavenging free ROS (reactive oxygen species) and reactive nitrogen species Preclinical 141
68 Antioxidant agent DPPH radical By preventing the formation of ROS (reactive oxygen species) Preclinical 142
69 Antioxidant agent ABTS method By neutralising free radicals Preclinical 143
70 Antioxidant agent DPPH, H2O2, and NO assay By scavenging free ROS (reactive oxygen species) Preclinical 144