Compilation of ongoing research on thiophene derivatives for the development of anti-oxidant agents.
Compound code | Indication | Biological target assay | Mechanism | Status | Ref. |
---|---|---|---|---|---|
66 | Antioxidant agent | DNA damage caused by bleomycin | By scavenging free ROS (reactive oxygen species) and reactive nitrogen species | Preclinical | 140 |
67 | Antioxidant agent | DNA damage caused by bleomycin | By scavenging free ROS (reactive oxygen species) and reactive nitrogen species | Preclinical | 141 |
68 | Antioxidant agent | DPPH radical | By preventing the formation of ROS (reactive oxygen species) | Preclinical | 142 |
69 | Antioxidant agent | ABTS method | By neutralising free radicals | Preclinical | 143 |
70 | Antioxidant agent | DPPH, H2O2, and NO assay | By scavenging free ROS (reactive oxygen species) | Preclinical | 144 |