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. 2019 Mar 1;7(2):10.1128/microbiolspec.psib-0006-2018. doi: 10.1128/microbiolspec.psib-0006-2018

TABLE 1.

List of available T4aP structuresa

Pseudomonas equivalent Name Species PDB (EMDB) code(s) Reference(s)
The pilus fiber
 PilY1 PilY1 Pseudomonas aeruginosa PAO1 3HX6 51
 PilV Tt1218 Thermus thermophilus 5G25 16
 PilW Tt1219 Thermus thermophilus 5G23, 5G24 16
 FimU FimU Pseudomonas aeruginosa PAO1 4IPU, 4IPV 39
 PilE PilE Pseudomonas aeruginosa PAO1 4NOA 40
PilX Neisseria meningitidis 2OPD, 2OPE 45
PilV Neisseria meningitidis 5V23,b 5V0Mb None
 PilA PilA Acinetobacter baumannii 4XA2, 5VAW,b 5IHJ, 5CFV 8
PilA Geobacter sulfurreducens 2M7G 19
PilA Pseudomonas aeruginosa PAK 1DZO, 1OQW, 1X6P/Q/R/X/Y/Z 6, 12, 17
PilA Pseudomonas aeruginosa K122-4 1HPW, 1QVE, 1RG0 14, 21
PilA Pseudomonas aeruginosa Pa110594 JYZ, 3JZZ 5
PilA Pseudomonas aeruginosa consensus 2PY0 11
PilA1 Clostridium difficile 4TSM, 4OGM, 4PE2 9
FimA Dichelobacter nodosus 3SOK 10
PilBac1 Shewanella oneidensis 4D40, 4US7 15
PilE Francisella tularensis 3SOJ 10
PilE Neisseria gonorrhoeae 1AY2, 2HI2, 2PIL 7, 13, 18
PilE Neisseria meningitidis 5JW8, 4V1Jb 29
Tt1221 Thermus thermophilus HB8 4BHR 94
 PilA fiber PilA Pseudomonas aeruginosa PAK 5VXY (8740) 30
PilA4 Thermus thermophilus None (3024) 119
PilE Neisseria gonorrhoeae 5VXX (8739) 30
PilE Neisseria gonorrhoeae 2HIL (1236) 7
PilE Neisseria meningitidis 5KUA (8287) 29
 None known ComP Neisseria meningitidis 2M3K, 5HZ7 38, 48
ComP Neisseri subflava 2NBA 38
PilJ Clostridium difficile 4IXJ 37
Tt1222 Thermus thermophilus HB8 5G2F 16
The motor
 PilB PilB Geobacter metallireducens 5TSG, 5TSH 60
PilF Thermus thermophilus 5IT5, 6EJF (3882), 6F8L (4194), (2222), (2223) 59, 62, 130
PilB Geobacter sulfurreducens 5ZFR 61
 PilB (N1D) MshE Vibrio cholerae serotype O1 5HTL 69
 PilT PilT Pseudomonas aeruginosa PAO1 3JVU, 3JVV 88
PilT Aquifex aeolicus strain VF5 2EWV, 2EWW, 2EYU, 2GSZ 89
PilT4 Geobacter sulfurreducens 5ZFQ 61
PilT2 Thermus thermophilus 5FL3b None
 PilC PilC Thermus thermophilus 2WHN 54
 FimX FimX Pseudomonas aeruginosa PAO1 4AG0, 3HV9, 3HVA, 3HV8, 4AFY, 4J40 135, 136
FimX Xanthomonas sp. 4FOK, 4F3H 76, 137
 PilZ PilZ Xanthomonas sp. 3CNR, 3DSG 75, 138
 FimX and PilZ FimX and PilZ Xanthomonas sp. 4FOU, 4F48 76, 137
The alignment complex
 PilM PilM Pseudomonas aeruginosa PAO1 5EOX, 5EOY, 5EQ6 55
 PilM and PilNcyto PilM and PilNcyto Pseudomonas aeruginosa PAO1 5EOU 55
PilM and PilNcyto Thermus thermophilus 2YCH 92
 PilN PilN Thermus thermophilus 4BHQ 94
 PilO PilO Pseudomonas aeruginosa PAO1 2RJZ, 5UVR 95, 96
 PilMN, PilMNO, and PilMNOA PilMN, PilMNO, and PilMNOA Thermus thermophilus Nonec (4157, 4157, 4159) 94
 PilP PilP Pseudomonas aeruginosa PAO1 2LC4, 2Y4X,b 2Y4Yb 100
PilP Neisseria meningitidis 2IVW 99
The outer membrane pore
 PilQ PilQ Pseudomonas aeruginosa PAO1 None (8297) 114
PilQ Thermus thermophilus Nonec (3985, 3995, 3996, 3997, 3998) 113
PilQ Candidatus pelagibacter None (8330) 117
 PilQ and PilP PilQ and PilP Neisseria meningitidis 4AV2 (2105) 101
 PilQ (N0 and linker from N0 to N1) PilQ (N0 and linker from N0 to N1) Neisseria meningitidis 4AR0 101
 PilQ (AMIN) PilQ (β2) Neisseria meningitidis 4AQZ 101
 PilF PilF Pseudomonas aeruginosa PAO1 2HO1, 2FI7 134, 139
 PilF PilW Neisseria meningitidis 2VQ2 126
 FimV FimV Pseudomonas aeruginosa PAO1 4MBQ, 4MAL 140
In situ structures of the T4aP Myxococcus xanthus 3JC8, 3JC9 (3247–3264) 43
Thermus thermophilus None (8224, 3021–3024) 118, 119
a

These are the published T4aP structures, not those from related T2SS, T4bP, Com pilus, Tad/Flp pilus, or archaellum.

b

Peer-reviewed article describing the structure has not been published yet.

c

A model could be built into the density, but the model was not published to the Protein Data Bank.