Table 2. Laboratory analyses available for clinical management.

Variable	MATERNAL GROUPS (N=185)			P value
	PPROM (+) AF infection n=61	PPROM (−) AF infection n=62	PPROM No Amniocentesis n=62
Maternal hematology
Hematocrit, g/dL ‡	32.9 [30.1–34.7]	34.6 [32.0–36.8]	33.7 [31.6–36.1]	0.006
Hemoglobin, g/dL ‡	11.3 [10.1–11.9]	11.8 [11.2–12.5]	11.8 [10.8–12.4]	0.003
WBC count, x1,000 cells/μL ‡	13.1 [10.7–17.0]	11.8 [9.8–14.5]	12.4 [10.8–15.3]	0.084
Neutrophils, % ‡	78.0 [71.5–85.5]	75.0 [71.0–81.5]	75.5 [69.0–82.0]	0.181
Lymphocytes, % ‡	13.0 [7.0–19.0]	16.0 [11.0–20.0]	16.5 [12.0–20.2]	0.050
Platelets, x1,000 cells/μL ‡	260 [194.5–302.5]	264.5 [198.0–306.0]	267.5 [218.8–318.0]	0.550
Amniotic fluid analysis results
Glucose, mg/dL ‡	6 [2–15]	26 [19–37]	NA	<0.001
LDH activity, U/L ‡	571 [277–1,175]	164 [110–328]	NA	<0.001
WBC, cells/mm3 ‡	387 [50–1,940]	13 [4–85]	NA	<0.001
Positive Gram stain §	39 (64)	0 (0)	NA	<0.001
Positive cultures §	58 (95)	0 (0)	NA	<0.001
Intra-amniotic infection (positive culture or positive Gram stain) §	61 (100)	0 (0)	NA	<0.001

^‡Data presented as median [interquartile range] and analyzed by Mann Whitney Ranks Sum test;

^§Data presented as n (%) and analyzed by Chi square tests;

P values in bold font are considered significant based on P<0.05.

Abbreviations: PPROM, preterm premature rupture of membranes; IAI, intra-amniotic inflammation; WBC, white blood cell; LDH, lactate dehydrogenase; MR score: mass restricted score