Table 3. Cord blood gas analyses and placental pathology results.
| Variable | MATERNAL GROUPS (N=185) | P value | ||
|---|---|---|---|---|
| PPROM (+) AF infection n=61 |
PPROM (−) AF infection n=62 |
PPROM No Amniocentesis n=62 |
||
| Cord blood gas analysis | n=40 | n=34 | n=44 | |
| Arterial pH ‡ | 7.32 [7.27–7.33] | 7.30 [7.23–7.33] | 7.28 [7.24–7.34] | 0.281 |
| Arterial base deficit, mmols/L ‡ | 4.9 [3.3–6.4] | 4.2[2.7–7.5] | 6.0[3.0–8.0] | 0.791 |
| Venous pH ‡ | 7.36 [7.31–7.39] | 7.36 [7.32–7.39] | 7.35 [7.31–7.38] | 0.437 |
| Venous base deficit, mmols/L ‡ | 4.2 [2.5–5.9] | 3.5 [2.2–5.6] | 4.0 [2.0–7.0] | 0.746 |
| Any cord pH < 7 § | 0 (0) | 1 (3) | 0 (0) | 0.288 |
| Placental pathology | n=61 | n=62 | n=60 | |
| Amniochorion, grade ‡ | 2 [1–3] | 0 [0–1] | 0 [0–2] | <0.001 |
| Amniochorion (grade 2–4) § | 25 (74) | 14 (23) | 26 (43) | <0.001 |
| Chorionic plate, stage ‡ | 3 [2–3] | 0 [0–2] | 2 [0–3] | <0.001 |
| Chorionic plate (stage II-III) § | 50 (82) | 22(35) | 35 (57) | <0.001 |
| Funisitis, grade ‡ | 2 [0–4] | 0 [0–1] | 0 [0–4] | <0.001 |
| Funisitis (grade 1–4) § | 41 (67) | 17 (27) | 30 (49) | <0.001 |
| Maternal HCA § absent mild severe |
12(20) 19(31) 30(49) |
45(73) 9(15) 8(12) |
34(56) 13(21) 14(23) |
<0.001 |
| Fetal HCA § absent mild severe |
5(8) 6(10) 50(82) |
35(56) 5(8) 22(36) |
24(39) 0(0) 37(61) |
<0.001 |
| Evidence of decidual hemorrhage or abruption § | 5(8) | 11(18) | 8(13) | 0.291 |
Data presented as median [interquartile range] and analyzed by Mann Whitney Ranks Sum test;
Data presented as n (%) and analyzed by Chi square tests;
P values in bold font are considered significant based on P<0.05.
Abbreviations: PPROM, preterm premature rupture of membranes; IAI, intra-amniotic inflammation; HCA, histologic chorioamnionits.