. Author manuscript; available in PMC: 2024 Nov 25.

Published in final edited form as: Fetal Diagn Ther. 2016 Oct 29;42(2):99–110. doi: 10.1159/000450997

Table 4. Results of newborn hematologic indices used clinically for neonatal sepsis workup.

Variable	MATERNAL GROUPS (N=185)			P value
Variable	PPROM (+) AF infection n=61	PPROM (−) AF infection n=62	PPROM No Amniocentesis n=62	P value
*Hematologic indices*
Hematocrit, % ^‡	45 [41–48]	48 [44–53]	47 [41–51]	0.007
Hemoglobin, g/dL ^‡	14 [13–15]	16 [14–17]	15 [14–17]	0.002
WBC count, cells x 1,000/mm³ ^‡	13 [8–18]	10 [8–14]	12 [9–16]	0.047
Platelet count, cells x 1,000/mm³ ^‡	260 [219–308]	286 [214–331]	252 [189–306]	0.172
Segmented neutrophils, % ^‡	36 [22–43]	35 [26–42]	40 [22–49]	0.292
Lymphocytes, % ^‡	38 [25–54]	45 [33–59]	38 [31–55]	0.094
Nucleated RBC, cells per 100 WBC ^‡	17 [9–43]	8 [4–17]	11 [5–25]	<0.001
ANC, cells/mm³ ^‡	3913 [2005–7762]	3157 [2378–5863]	5236 [1995–8112]	0.286
ABC, cells/mm³ ^‡	682 [252–2388]	132 [0–592]	270 [0–976]	<0.001
I:T ratio, % ^‡	8 [2–13]	1 [0–5]	2 [0–8]	<0.001
Presumed EONS ^§	22 (37)	8 (13)	10 (17)	0.004
Culture confirmed EONS ^§	2 (3)	1 (2)	1 (2)	0.779

^‡

Data presented as median [interquartile range] and analyzed by Kruskal-Wallis ANOVA.

^§

Data presented as n (%) and analyzed by Chi square tests.

Abbreviations: PPROM, preterm premature rupture of membranes; IAI, intra-amniotic inflammation; WBC, white blood cell; RBC, red blood cells; ANC= absolute neutrophil count; ABC= absolute band count; I:T, immature/total neutrophil count; EONS: early-onset neonatal sepsis.