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IAP family members and survivin. (A) Linear domain structures of all eight IAP family members. (B) Crystal structure of survivin as a homodimer (PDB code: 1F3H). (C) Survivin function in extrinsic and intrinsic apoptosis. Fas L, Fas ligand; TRAIL, TNF-related apoptosis-inducing ligand; Cyto c, cytochrome c.
