TABLE 1.

Aβ_1-42 uptake in NC-HEK293 T, OATP1A2-HEK293T and human astrocytes assessed through flow cytometry.

	24 h	48 h	72 h
NC-HEK293T (Aβ1-42 0 μM)	0.30 ± 0.04	0.33 ± 0.09	0.33 ± 0.04
NC-HEK293T (Aβ1-42 0.4 μM)	7.13 ± 2.60**	12.83 ± 1.50**	16.87 ± 0.12**
NC-HEK293T (Aβ1-42 1 μM)	13.45 ± 2.02**	19.15 ± 0.63**	25.02 ± 0.36**
NC-HEK293T (Aβ1-42 2.5 μM)	21.18 ± 0.62**	28.76 ± 3.09**	32.84 ± 3.19**
HEK293T- OATP1A2 (Aβ1-42 0 μM)	0.28 ± 0.03	0.25 ± 0.09	0.27 ± 0.04
HEK293T- OATP1A2 (Aβ1-42 0.4 μM)	9.43 ± 0.77**	23.40 ± 2.17**	31.37 ± 4.27**
HEK293T- OATP1A2 (Aβ1-42 1 μM)	20.27 ± 0.49**	35.11 ± 2.01**	54.01 ± 2.71**
HEK293T- OATP1A2 (Aβ1-42 2.5 μM)	26.83 ± 4.77**	49.41 ± 3.32**	59.00 ± 1.57**
HNA (Aβ1-42 0 μM)	0.41 ± 0.05	0.33 ± 0.05	0.39 ± 0.05
HNA (Aβ1-42 0.4 μM)	6.47 ± 1.86**	13.42 ± 0.58**	32.91 ± 2.06**
HNA (Aβ1-42 1 μM)	11.87 ± 0.31**	28.80 ± 1.93**	40.89 ± 2.17**
HNA (Aβ1-42 2.5 μM)	23.75 ± 0.62**	44.47 ± 0.88**	48.11 ± 2.50**

(Mean ± SD, n = 3, *p < 0.05; **p < 0.01) HNA: human astrocytes.