Figure 2.

Model of required protein domains for the classification of WAK and WAKL proteins. (A) Model of the protein domain architecture of WAK proteins. The five domains required are a signal peptide (SP) at the N-terminal (grey), a galacturonan-binding domain (GUB_WAK_Bind; yellow), one to three extracellular epidermal growth factor (EGF)-like domains or EGF_Ca (blue), a transmembrane (TM) domain (Red) and a cytoplasmic Ser/Thr kinase (STK) domain (also known as a pkinase domain at the C-terminal; green). (B) Model of the different combinations of protein domains that make up WAKL proteins. They must contain an STK domain and a GUB_WAK_bind domain, but the other domains are variable. (Created with BioRender.com).