Fig. 1. ZRSR2 mutations, co-mutations and clonal dynamics with treatment.

A Representation of ZRSR2 mutations detected, positioned on the ZRSR2 protein and its functional domains. B The co-mutational pattern in 164 ZRSR2m MN patients. A column represents each patient. C Fishplot showing the progression of mutations VAF in ZRSR2m MDS patients throughout disease course and therapy.