Figure 7.

Neutrophil depletion impedes ALκ(TAL) resolution in vivo. Immunodeficient mice were implanted with Dylight800 labeled ALκ(TAL) amyloidomas and fluorescence measured over time (A, B, D, E),. 18 days post-implantation, amyloidomas were extracted, and amyloid area was determined by ImageJ (C). Mice received either the anti-Ly6G (1A8) neutrophil depletion antibody or vehicle control treatment. Data is representative of 2 experiments with 8-12 mice per group. Statistical significance was determined by unpaired Student’s t-test *p<0.05, **p<0.01, ***p<0.001.