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. 2024 Jul 24;271(12):7402–7421. doi: 10.1007/s00415-024-12576-x
Recommendation to change anti-parkinsonian medication in the management of psychosis in Parkinson’s disease (new)

In the event of psychotic symptoms in people with PD, medication should be adjusted as follows:

1) Dose reduction of anti-parkinsonian medication

2) Simplification of combination treatments

3) Reduction/discontinuation should follow this sequence: Anticholinergics > Amantadine > MAO-B inhibitors > Dopamine agonists > COMT inhibitors

Level of consensus: 100%, strong consensus