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. 2024 Nov 25;15:709. doi: 10.1007/s12672-024-01572-2

Table 2.

DHFR modulates the sensitivity of HCC cells to molecularly targeted agents

Groups IC50 values of Sorafenib on MHCC97-H cells (μmol/L)
Control 1.02
DHFR 5.38
siDHFR 0.13
DHFR + miRNA-34a 0.25
siDHFR + NICD 5.67