Table 3.

The effect of the metabolism or clearance of antitumor drugs in MHCC97-H cells

Groups		Sorafenib	Adriamycin
		t1/2 values (hours)
Control		18.78	13.25
Pralatrexate	0.5	19.62	14.10
	1	20.42	16.45
	2	23.71	17.97
Fatostatin	0.1	18.39	14.01
	1	18.59	13.83
BAY-876	0.1	18.24	13.22
	1	18.32	13.48
Rifampicin	1	13.67	10.73
	10	9.34	5.94
Ketoconazole	1	22.49	19.52
	10	30.53	27.18