Table 4.

Overexpression of NICD almost blocked the effect of Pralatrexate on sorafenib in MHCC97-H cells

Groups	Pralatrexate	sorafenib
		IC50 values (μmol/L)
Control	–	1.15
	0.5	0.36
	1	0.10
	2	0.02
NICD	–	4.88
	0.5	4.85
	1	4.68
	2	4.55