A: Cranium scanning in C57BL/6J mice via laser Doppler imaging before and at 2, 7, and 28d after BCAS; B: Cerebral blood flow rate (average postoperative perfusion unit/preoperative perfusion unit×100%) before and at 2, 7, and 28d after BCAS. n=5. aP<0.05, bP<0.01 vs preoperatively using one-way analysis of variance. BCAS: Bilateral carotid artery stenosis.