A: Differential expression of HIF-1α, GFAP, Bcl-2, caspase-3, and β-actin in the retina of sham and BCAS mice after 2, 7, and 28d; B-E: Quantitative analysis of the expressions of HIF-1α, GFAP, BCL-2, and caspase-3 normalized according to β-actin expression at postoperative days 2, 7, 14, and 28; n=5 in each group, aP<0.05, bP<0.01 between the sham group and the BCAS group (Student's t-test). BCAS: Bilateral carotid artery stenosis; HIF: Hypoxia-inducible factor; GFAP: Glial fibrillary acidic protein.