Skip to main content
. 2001 Mar;75(6):2710–2728. doi: 10.1128/JVI.75.6.2710-2728.2001

TABLE 1.

Inhibition of p38MAPK decreases viral yielda

Treatment Viral yield (PFU, 107)b at:
18 h 24 h 28 h 32 h
DMSO 6.5 ± 0.3 12 ± 1 21 ± 1 17 ± 1
SB203580 6.0 ± 0.3 8.0 ± 0.4 8.9 ± 0.4 7.7 ± 0.4
a

Cells (5 × 106) were pretreated with 30 μM SB203580 or DMSO for 1 h and infected with wt HSV-1 in the continuous presence of SB203580 or DMSO. 

b

Viral yields were determined at 18, 24, 28, and 32 h postinfection. Each value represents the mean ± standard deviation from three independent experiments, and in each experiment triplicate determinations were performed.