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Acquired ctDNA gene mutations in patients with disease progression (n = 29)
| Patients, n | Gene | Mutation |
|---|---|---|
| 3 | TP53 | Y234C, S241C, R273C |
| 1 | HER2 | D769H |
| 1 | BRAF | V600E, V600M |
| 1 | CASP8 | F338fs |
| 1 | CIC | T2002fs |
| 1 | GRIN2A | Q201* |
| 1 | JAK1 | L1114fs |
| 1 | KEAP1 | F64fs |
| 1 | KMT2D | L671fs |
| 1 | NOTCH2 | N396fs |
| 1 | PIK3CA | R88Q |
ctDNA, circulating tumor DNA.
