Table 3.
Most common adverse events in 35 participants (maximum grade per patient per event)
| Adverse event | Any grade, n (%) | Grade 3 or 4, n (%) |
|---|---|---|
| Hematologic toxicity | ||
| Anemia | 18 (51.4) | 6 (17.1) |
| Thrombocytopenia | 15 (42.9) | 3 (8.6) |
| Neutropenia | 27 (77.1) | 12 (34.3) |
| Febrile neutropenia | 0 | 0 |
| Non-hematologic toxicity | ||
| Nausea | 33 (94.3) | 0 |
| Vomiting | 10 (28.6) | 0 |
| Diarrhea | 6 (17.1) | 1 (2.9) |
| Constipation | 0 | 0 |
| Hypertension | 4 (11.4) | 0 |
| Fatigue | 29 (82.9) | 1 (2.9) |
| Hand-foot syndrome | 0 | 0 |
| Proteinuria | 4 (11.4) | 0 |
| ALT/AST increased | 8 (22.9) | 1 (2.9) |