Table 4.

Cohen’s Kappa coefficients from the evaluation by artificial intelligence compared by the mode from 5 embryologist of the three features of blastocysts: grade of expansion, inner cell mass and trophectoderm

Morphological feature	Class 2	Class 3	Class 4	Average
Blastocyst expansion
Kappa	0.751 (0.620-0.883)	0.652 (0.521-0.783)	0.790(0.659-0.921)	0.729(0.632-0.826)
P value	<0.001	<0.001	<0.001	<0.001
Inner cell mass	Grade A	Grade B	Grade C	Average
Kappa	0.779 (0.648-0.910)	0.688 (0.558-0.818)	0.681(0.551-0.811)	0.705 (0.606-0.804)
P value	<0.001	<0.001	<0.001	<0.001
Trophectoderm	Grade A	Grade B	Grade C	Average
Kappa	0.382(0.256-0.507)	0.402 (0.273-0.531)	0.501 (0.370-0.631)	0.438(0.332-0.544)
P value	<0.001	<0.001	<0.001	<0.001

Kappa values are expressed with confidence intervals (CI) 95% between brackets. Class 2; Early blastocyst, Class 3; Full blastocyst, and Class 4; Expanded blastocyst.