5. Separating indirect from direct evidence: adverse events.

Treatment comparison	Proportion of direct evidence	RoR	P value
Dobutamine versus levosimendan, only indirect evidence	0	NA	NA
Dobutamine versus milrinone, only direct evidence	1	NA	NA
Dobutamine versus milrinone LD, only indirect evidence	0	NA	NA
Dobutamine versus placebo, only indirect evidence	0	NA	NA
Levosimendan versus milrinone	0.88	1.2788	0.6764
Levosimendan versus milrinone LD, only indirect evidence	0	NA	NA
Levosimendan versus placebo	0.2	0.782	0.6764
Milrinone versus milrinone LD	0.87	0.8494	0.8505
Milrinone versus placebo	0.92	1.2788	0.6764
Milrinone LD versus placebo	0.83	0.8627	0.8505

Separation of indirect from direct evidence using a back‐calculation method, random‐effects model
RoR: ratio of ratios (direct/indirect), with P value of test for disagreement

Abbreviations
LD: low dose; NA: not applicable; RoR: ratio of ratios