Figure 3.

Detection of the helix region (yellow) and the β-sheet region (cyan) on the box-cropped cryo-EM density map (EMD-4141 cropped at chain B of PDB-5M1S). (A) Atomic structure (ribbon) on the corresponding cropped density map, indicating the helices (blue) and the β-sheets (magenta) of chain B of 5M1S (PDB-ID). (B) to (F) show the helix regions (yellow) and the β-sheet regions (cyan) that were detected via CNN models trained using CE, FL, DL, CE_DL, and FL_DL, respectively. The red arrows indicate the undetected or wrongly detected regions, and the black arrows, the better-detected corresponding regions.